Download Files:
Products Details
Product Description
– hAChE/Aβ1-42-IN-1 (Compound 16) is a potent inhibitor of hAChE and Aβ1-42 aggregation. hAChE/Aβ1-42-IN-1 shows acceptable relative safety upon hepG2 cell line and excellent BBB penetration with wide safety margin. hAChE/Aβ1-42-IN-1 has the potential for the research of Alzheimer disease (AD)[1].
Web ID
– HY-144389
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C20H24N6O
References
– [1]Waly OM, et al. Synthesis, biological evaluation, and molecular modeling simulations of new heterocyclic hybrids as multi-targeted anti-Alzheimer’s agents. Eur J Med Chem. 2022;231:114152.
CAS Number
– 2761149-17-9
Molecular Weight
– 364.44
SMILES
– O=C(NC1=NNC2=NC=CC=C21)CCN3CCN(CC3)CC4=CC=CC=C4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Amyloid-β;Cholinesterase (ChE)
Isoform
– AChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
