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HA-IN-1
SKU
HY-155514-Get quote
Category Reference compound
Tags Anti-infection, Inflammation/Immunology, Influenza Virus
Products Details
Product Description
– HA-IN-1 (compound 5g) is a Hemagglutinin (HA) ligand with high affinity, targeting to the trypsin cleavage site of HA. HA-IN-1 inhibits HA-mediated membrane fusion and reduces the pulmonary virus titer in vivo. HA-IN-1 is a potential influenza A virus (IAV) inhibitor, and an anti-influenza agent[1].
Web ID
– HY-155514
Shipping
– Room temperature
Molecular Formula
– C42H35NO6
References
– [1]Li B, et al. Design, synthesis, and biological evaluation of novel penindolone derivatives as potential inhibitors of hemagglutinin-mediated membrane fusion. Eur J Med Chem. 2023 Oct 5;258:115615.
Molecular Weight
– 649.73
SMILES
– CC1=CC(C(C)=O)=C(O)C(CC2=C(CC3=C(O)C(C)=CC(C(C)=O)=C3O)C4=CC(C5=C6C(C=CC=C6)=CC7=C5C=CC=C7)=CC=C4N2)=C1O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Influenza Virus
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.