Products Details

Product Description

– H4R antagonist 3 (Example 18) is a histamine-4 receptor antagonist with an EC50 of <10 mM. H4R antagonist 3 can be used for the research of prevention of inflammatory, autoimmune, allergic, and ocular diseases[1].

Web ID

– HY-156667

Shipping

– Room temperature

Molecular Formula

– C19H21ClN4S

References

– [1]Allen J. Borchardt, et al. Aminopyrimidine inhibitors of histamine receptors for the treatment of disease. Patent US20100063047A1.

CAS Number

– 1003091-20-0

Molecular Weight

– 372.91

SMILES

– ClC1=CC=C(C2=CSC3=NC=NC(N(C4CCN(CC4)C)C)=C32)C=C1

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– Histamine Receptor

Pathway

– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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