H4 Receptor antagonist 1

$90$850

Products Details

Product Description

– H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.

Web ID

– HY-114025

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neuromodulation

Molecular Formula

– C16H17ClN4O

References

– [1]Cramp S, et al. Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2516-9.

CAS Number

– 848217-00-5

Molecular Weight

– 316.79

Compound Purity

– 99.66

SMILES

– CN1CCN(C2=C(OC3=CC=C(Cl)C=C34)C4=NC(C)=N2)CC1

Clinical Information

– No Development Reported

Research Area

– Neurological Disease; Endocrinology

Solubility

– DMSO : 10 mg/mL (ultrasonic)

Target

– Histamine Receptor

Isoform

– H4 Receptor

Pathway

– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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