Download Files:
H2L 5765834
$71 – $1,350
Products Details
Product Description
– H2L 5765834 is an antagonist of lysophosphatidic acid receptors LPA1, LPA3, and LPA5, with IC50s of 94, 752, and 463 nM respectively[1].
Web ID
– HY-15706
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H12N2O7
References
– [1]Williams JR, et, al. Unique ligand selectivity of the GPR92/LPA5 lysophosphatidate receptor indicates role in human platelet activation. J Biol Chem. 2009 Jun 19; 284(25): 17304-19.|[2]Bae GH, et, al. Lysophosphatidic acid protects against acetaminophen-induced acute liver injury. Exp Mol Med. 2017 Dec 8; 49(12): e407.
CAS Number
– 420841-84-5
Molecular Weight
– 404.33
Compound Purity
– 98.36
SMILES
– O=C(C1=CC2=C(C(N(C3=CC=CC(OC4=CC=C([N+]([O-])=O)C=C4)=C3)C2=O)=O)C=C1)O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– LPL Receptor
Isoform
– LPAR1;LPAR3;LPAR5
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
