Download Files:
Products Details
Product Description
– H1k, a Eudistomin Y derivative, is a lysosome-targeted antiproliferation agent. H1k increases the autophagy signal and downregulate the expression of cyclin-dependent kinase (CDK1) and cyclin B1. H1k can be used in research of cancer[1].
Web ID
– HY-149261
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C26H20N2O2
References
– [1]Yang G, et, al. Design, synthesis, and discovery of Eudistomin Y derivatives as lysosome-targeted antiproliferation agents. Eur J Med Chem. 2023 Mar 15;250:115193.
Molecular Weight
– 392.45
SMILES
– COC1=CC=C(C=C1)CN2C3=C(C4=C2C(C(C5=CC=CC=C5)=O)=NC=C4)C=CC=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Autophagy;CDK
Pathway
– Autophagy;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
