Products Details

Product Description

– H-L-Tyr(3-N3)-OH is a click chemistry reagent containing an azide[1]. H-L-Tyr(3-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Web ID

– HY-151675

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C9H10N4O3

References

– [1]Yokogawa T, et al. Incorporation of 3-azidotyrosine into proteins through engineering yeast tyrosyl-tRNA synthetase and its application to site-selective protein modification. Methods Mol Biol. 2010;607:227-42.

CAS Number

– 129960-90-3

Molecular Weight

– 222.20

SMILES

– OC([C@@H](N)CC1=CC(N=[N+]=[N-])=C(C=C1)O)=O

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– 10 mM in DMSO

Target

– ADC Linker

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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