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GW297361
$340 – $1,350
Products Details
Product Description
– GW297361 is an oxindole CDK inhibitor that elicits a Pho85-selective response in cells. GW297361 inhibits yeast Cdk1 and Pho85 with IC50s of 20 nM and 400 nM in vitro, respectively[1].
Web ID
– HY-153556
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– C16H12N4O3S2
References
– [1]Kung C, et al. Selective kinase inhibition by exploiting differential pathway sensitivity. Chem Biol. 2006 Apr;13(4):399-407.
CAS Number
– 388627-21-2
Molecular Weight
– 372.42
Compound Purity
– 98.13
SMILES
– O=S(C1=CC=C(N/C=C(C2=C(SC=N3)C3=CC=C2N4)C4=O)C=C1)(N)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– CDK;Src;VEGFR
Isoform
– CDK1;CDK2;CDK4;CDK9;Pho85;VEGFR2/KDR/Flk-1
Pathway
– Cell Cycle/DNA Damage;Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
