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Products Details
Product Description
– Guanylyl Imidodiphosphate (Guanosine 5′-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies[1][2][3].
Web ID
– HY-100767
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C10H17N6Na3O13P3
References
– [1]Mitsunori Kawato, et al. Regulation of platelet dense granule secretion by the Ral GTPase-exocyst pathway. J Biol Chem. 2008 Jan 4;283(1):166-174.|[2]J Goldberg, et al. Structural basis for activation of ARF GTPase: mechanisms of guanine nucleotide exchange and GTP-myristoyl switching. Cell. 1998 Oct 16;95(2):237-48.|[3]C Gaudin, et al. Overexpression of Gs alpha protein in the hearts of transgenic mice. J Clin Invest. 1995 Apr;95(4):1676-83.
CAS Number
– 148892-91-5
Molecular Weight
– 591.16
SMILES
– O[C@H]1[C@](O[C@@H]([C@H]1O)COP(OP(NP(O)(O)=O)(O)=O)(O)=O)([H])N2C3=C(C(N=C(N3)N)=O)N=C2.[Na].[Na].[Na]
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– 10 mM in DMSO
Target
– Adenylate Cyclase
Pathway
– GPCR/G Protein
Product type
– Biochemical Assay Reagents
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
