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Products Details
Product Description
– GSK894281 is an orally active and highly potent ghrelin receptor full agonist with a pEC50 of <4.9 at the human motilin receptor. GSK894281 effectively enters the CNS. GSK894281 has the potential for constipation or to assist in emptying the colon prior to colonoscopy or colon surgery research[1].
Web ID
– HY-111232
Shipping
– Room temperature
Molecular Formula
– C24H28FN3O4S
References
– [1]A D Shafton, et al.Oral administration of a centrally acting ghrelin receptor agonist to conscious rats triggers defecation. Neurogastroenterol Motil. 2009 Jan;21(1):71-7.
CAS Number
– 874958-63-1
Molecular Weight
– 473.56
SMILES
– O=S(NC1=CC(N2C[C@H](N[C@H](C2)C)C)=CC=C1OC)(C3=CC(F)=C(C4=CC=C(O4)C)C=C3)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– GHSR
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
