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GSK8612
$50 – $825
Products Details
Product Description
– GSK8612 is a highly selective and potent Tank-binding Kinase-1 (TBK1) inhibitor, with a pIC50 of 6.8 for recombinant TBK1[1].
Web ID
– HY-111941
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C17H17BrF3N7O2S
References
– [1]Thomson DW, et al. Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor. ACS Med Chem Lett. 2019 Mar 11;10(5):780-785.
CAS Number
– 2361659-62-1
Molecular Weight
– 520.33
Compound Purity
– 99.33
SMILES
– NS(C1=CC=C(CNC2=C(Br)C=NC(NC3=CN(CC(F)(F)F)N=C3C)=N2)C=C1)(=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology; Neurological Disease
Solubility
– DMSO : ≥ 125 mg/mL
Target
– IKK
Isoform
– TBK1
Pathway
– NF-κB
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
