GSK369796 Dihydrochloride

$132$1,320

Products Details

Product Description

– GSK369796 Dihydrochloride is an affordable and effective antimalarial and inhibits hERG potassium ion channel repolarization with an IC50 of 7.5 μM.

Web ID

– HY-12082A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C20H24Cl3N3O

References

– [1]O’Neill PM, et al. Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century. J Med Chem. 2009 Mar 12;52(5):1408-15.

CAS Number

– 1010411-21-8

Molecular Weight

– 428.78

Compound Purity

– 98.32

SMILES

– OC1=CC(NC2=CC=NC3=CC(Cl)=CC=C23)=CC=C1CNC(C)(C)C.[H]Cl.[H]Cl

Clinical Information

– Phase 1

Research Area

– Infection

Solubility

– DMSO : 100 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)

Target

– Parasite;Potassium Channel

Isoform

– Plasmodium

Pathway

– Anti-infection;Membrane Transporter/Ion Channel

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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