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Products Details
Product Description
– GSK317354A is a ROCK and GRK inhibitor. GSK317354A can be used for heart failure and Parkinson’s disease research[1].
Web ID
– HY-111239
Shipping
– Room temperature
Molecular Formula
– C25H18F4N6O
References
– [1]Homan KT, et al. Identification and structure-function analysis of subfamily selective G protein-coupled receptor kinase inhibitors. ACS Chem Biol. 2015 Jan 16;10(1):310-9.
CAS Number
– 874119-13-8
Molecular Weight
– 494.44
SMILES
– O=C(C1=C(C)NC(C2=CC=C(C(F)(F)F)N=C2)=NC1C3=CC=C(F)C=C3)NC4=CC5=C(NN=C5)C=C4
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– G Protein-coupled Receptor Kinase (GRK);ROCK
Isoform
– ROCK
Pathway
– Cell Cycle/DNA Damage;Cytoskeleton;GPCR/G Protein;Stem Cell/Wnt;TGF-beta/Smad
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
