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Products Details
Product Description
– GSK2973980A is a potent and selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor with an IC50 of 3 nM.
Web ID
– HY-111417
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C25H19F5N4O4
References
– [1]Cheung M, et al. Discovery of Tetralones as Potent and Selective Inhibitors of Acyl-CoA:Diacylglycerol Acyltransferase 1. ACS Med Chem Lett. 2018 Jan 16;9(2):103-108.
CAS Number
– 2219321-25-0
Molecular Weight
– 534.43
SMILES
– FC1=C(F)C=C(NC(NC2=CN=C(C3=CC(CC[C@](CC(O)=O)(CC(F)(F)F)C4=O)=C4C=C3)C=N2)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Acyltransferase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
