GSK2556286

$400$3,400

Products Details

Product Description

– GSK2556286 (GSK286) is an orally active inhibitor of M. tuberculosis. GSK2556286 inhibits growth within human macrophages (IC50 = 0.07 μM). GSK2556286 is effective against both multidrug-resistant (MDR) or extensively drug-resistant (XDR) and agent-sensitive (DS) M. tuberculosis.

Web ID

– HY-147017

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C18H23N3O3

References

– [1]Nuermberger EL, et al. GSK2556286 Is a Novel Antitubercular Drug Candidate Effective In Vivo with the Potential To Shorten Tuberculosis Treatment. Antimicrob Agents Chemother. 2022 May 24:e0013222.

CAS Number

– 1210456-20-4

Molecular Weight

– 329.39

Compound Purity

– 99.89

SMILES

– O=C1C=C(CN2CCC(CC2)OC3=CC=CC(C)=C3C)NC(N1)=O

Clinical Information

– Phase 1

Research Area

– Infection; Inflammation/Immunology

Solubility

– DMSO : 3.33 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– Bacterial

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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