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GSK2236805
Products Details
Product Description
– GSK2236805 is a potent hepatitis C virus inhibitor with pEC50 values of 10.4, 11.1 for HCV genotype 1a (gt1a) and gt1b, respectively[1].
Web ID
– HY-12731
Shipping
– Room temperature
Molecular Formula
– C42H52N8O8
References
– [1]Kazmierski WM, et al. Novel spiroketal pyrrolidine GSK2336805 potently inhibits key hepatitis C virus genotype 1b mutants: from lead to clinical compound. J Med Chem. 2014 Mar 13;57(5):2058-73.
CAS Number
– 1256390-53-0
Molecular Weight
– 796.91
SMILES
– O=C(OC)N[C@H](C(N1[C@H](C2=NC(C3=CC=C(C4=CC=C(C5=CNC([C@H](C6)N(C([C@@H](NC(OC)=O)C(C)C)=O)CC76OCCO7)=N5)C=C4)C=C3)=CN2)CCC1)=O)C(C)C
Clinical Information
– Phase 1
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HCV
Pathway
– Anti-infection
Product type
– Reference compound
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