Products Details

Product Description

– GSK2236805 is a potent hepatitis C virus inhibitor with pEC50 values of 10.4, 11.1 for HCV genotype 1a (gt1a) and gt1b, respectively[1].

Web ID

– HY-12731

Shipping

– Room temperature

Molecular Formula

– C42H52N8O8

References

– [1]Kazmierski WM, et al. Novel spiroketal pyrrolidine GSK2336805 potently inhibits key hepatitis C virus genotype 1b mutants: from lead to clinical compound. J Med Chem. 2014 Mar 13;57(5):2058-73.

CAS Number

– 1256390-53-0

Molecular Weight

– 796.91

SMILES

– O=C(OC)N[C@H](C(N1[C@H](C2=NC(C3=CC=C(C4=CC=C(C5=CNC([C@H](C6)N(C([C@@H](NC(OC)=O)C(C)C)=O)CC76OCCO7)=N5)C=C4)C=C3)=CN2)CCC1)=O)C(C)C

Clinical Information

– Phase 1

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– HCV

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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