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GSK1838705A
$99 – $1,045
Products Details
Product Description
– GSK1838705A is a potent and reversible IGF-IR and the insulin receptor inhibitor with IC50s of 2.0 and 1.6 nM, respectively. It also inhibits ALK with an IC50 of 0.5 nM.
Web ID
– HY-13020
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C27H29FN8O3
References
– [1]Sabbatini P, et al.
GSK1838705A inhibits the insulin-like growth factor-1 receptor and anaplastic lymphoma kinase and shows antitumor activity in experimental models of human cancers.
Mol Cancer Ther. 2009 Oct;8(10):2811-20.
CAS Number
– 1116235-97-2
Molecular Weight
– 532.57
Compound Purity
– 99.14
SMILES
– FC1=C(C(NC)=O)C(NC2=C3C(NC=C3)=NC(NC4=CC5=C(CCN5C(CN(C)C)=O)C=C4OC)=N2)=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Endocrinology
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Anaplastic lymphoma kinase (ALK);IGF-1R;Insulin Receptor
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
