GSK1820795A

$200$4,300

Products Details

Product Description

– GSK1820795A, as a telmisartan analog, is a selective hGPR132a antagonist. GSK1820795A blocks activation of yeast cells expressing hGPR132a by N-acylamides[1]. GSK1820795A is also a angiotensin II antagonists and partial PPARγ agonists (compound 38)[2].

Web ID

– HY-111616

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Molecular Formula

– C35H34N8

References

– [1]Lamotte Y, Faucher N, Sançon J, et al. Discovery of novel indazole derivatives as dual angiotensin II antagonists and partial PPARγ agonists. Bioorg Med Chem Lett. 2014;24(4):1098-1103. |[2]Foster JR, et al. N-Palmitoylglycine and other N-acylamides activate the lipid receptor G2A/GPR132. Pharmacol Res Perspect. 2019;7(6):e00542.

CAS Number

– 2650253-86-2

Molecular Weight

– 566.70

Compound Purity

– 99.76

SMILES

– CCCN1C(CC2=CC=C(C3=C(C4=NNN=N4)C=CC=C3)C=C2)=C5C(C=CC(C6=NC(C=CC=C7)=C7N6CCCC)=C5)=N1

Clinical Information

– No Development Reported

Research Area

– Others

Solubility

– DMSO : 100 mg/mL (ultrasonic)

Target

– Angiotensin Receptor;PPAR

Isoform

– AT1 Receptor;PPARγ

Pathway

– Cell Cycle/DNA Damage;GPCR/G Protein;Vitamin D Related/Nuclear Receptor

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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