Download Files:
GSK1820795A
$200 – $4,300
Products Details
Product Description
– GSK1820795A, as a telmisartan analog, is a selective hGPR132a antagonist. GSK1820795A blocks activation of yeast cells expressing hGPR132a by N-acylamides[1]. GSK1820795A is also a angiotensin II antagonists and partial PPARγ agonists (compound 38)[2].
Web ID
– HY-111616
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C35H34N8
References
– [1]Lamotte Y, Faucher N, Sançon J, et al. Discovery of novel indazole derivatives as dual angiotensin II antagonists and partial PPARγ agonists. Bioorg Med Chem Lett. 2014;24(4):1098-1103. |[2]Foster JR, et al. N-Palmitoylglycine and other N-acylamides activate the lipid receptor G2A/GPR132. Pharmacol Res Perspect. 2019;7(6):e00542.
CAS Number
– 2650253-86-2
Molecular Weight
– 566.70
Compound Purity
– 99.76
SMILES
– CCCN1C(CC2=CC=C(C3=C(C4=NNN=N4)C=CC=C3)C=C2)=C5C(C=CC(C6=NC(C=CC=C7)=C7N6CCCC)=C5)=N1
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Angiotensin Receptor;PPAR
Isoform
– AT1 Receptor;PPARγ
Pathway
– Cell Cycle/DNA Damage;GPCR/G Protein;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
