Download Files:
GSK1790627
$260 – $2,100
Products Details
Product Description
– GSK1790627 is the N-deacetylated metabolite of Trametinib (HY-10999). Trametinib is an orally active MEK inhibitor, and activates autophagy and induces apoptosis[1].
Web ID
– HY-148507
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture and light)
Shipping
– Blue Ice
Molecular Formula
– C24H21FIN5O3
References
– [1]Ho MY, et al. Trametinib, a first-in-class oral MEK inhibitor mass balance study with limited enrollment of two male subjects with advanced cancers. Xenobiotica. 2014 Apr;44(4):352-68.
CAS Number
– 871701-87-0
Molecular Weight
– 573.36
Compound Purity
– 98.81
SMILES
– O=C1N(C2=CC=CC(N)=C2)C(C(C(N1C3CC3)=O)=C(NC4=CC=C(I)C=C4F)N5C)=C(C)C5=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Target
– MEK
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
