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GSK-3 inhibitor 1

SKU HY-13973A-1 mg Category Reference compound Tags GSK-3, Metabolic Disease, PI3K/Akt/mTOR;Stem Cell/Wnt

$130 – $1,900

Size1 mg

1 mg 5 mg 10mM/1mL 10 mg 25 mg 50 mg 100 mg

Products Details

Product Description

– GSK-3 inhibitor 1 (compound core 3) is a GSK-3 inhibitor that induces stem/progenitor cell self-renewal (e.g. induces stem/progenitor cell proliferation while maintaining the ability to differentiate into tissue cells in the progeny)[1][2].

Web ID

– HY-13973A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– Metabolism-sugar/lipid metabolism

Molecular Formula

– C22H17ClFN5O2

References

– [1]SOLUBILIZED COMPOSITIONS FOR CONTROLLED PROLIFERATION OF STEM CELLS / GENERATING INNER EAR HAIR CELLS USING GSK3 INHIBITORS: III. 20170252449 A1|[2]Christopher Loose, et al. 1h-pyrrole-2,5-dione compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells. Patent WO2018125746A1.

CAS Number

– 603272-51-1

Molecular Weight

– 437.85

Compound Purity

– 99.89

SMILES

– FC1=CC(CNCC2)=C(N2C=C3C4=C(C5=CN=C6N5C=CC=C6)C(NC4=O)=O)C3=C1.Cl

Clinical Information

– No Development Reported

Research Area

– Metabolic Disease

Solubility

– DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)

Target

– GSK-3

Isoform

– GSK-3

Pathway

– PI3K/Akt/mTOR;Stem Cell/Wnt

Product type

– Reference compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.