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Products Details
Product Description
– Griseofulvin-d3 is the deuterium labeled Griseofulvin. Griseofulvin (Gris-PEG) is a spirocyclic fungal natural product used in treatment of fungal dermatophytes; Antifungal agent[1][2].
Web ID
– HY-17583S
Shipping
– Room temperature
Molecular Formula
– C17H14D3ClO6
References
– [1]Schmeel LC, et al. Griseofulvin Efficiently Induces Apoptosis in In Vitro Treatment of Lymphoma and Multiple Myeloma. Anticancer Res. 2017 May;37(5):2289-2295.|[2]Brilhante RSN, et al. In vitro activity of azole derivatives and griseofulvin against planktonic and biofilm growth of clinical isolates of dermatophytes. Mycoses. 2018 Jul;61(7):449-454.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1279033-22-5
Molecular Weight
– 355.78
SMILES
– O=C1[C@]2(C(OC([2H])([2H])[2H])=CC(C[C@H]2C)=O)OC3=C(Cl)C(OC)=CC(OC)=C31
Clinical Information
– No Development Reported
Research Area
– Infection; Cancer
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Apoptosis;Endogenous Metabolite;Fungal;Isotope-Labeled Compounds
Pathway
– Anti-infection;Apoptosis;Metabolic Enzyme/Protease;Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
