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Products Details
Product Description
– GPS491 (EC50 = 0.47 μM) suppresses expression of the HIV-1 structural protein Gag and alters HIV-1 RNA accumulation, decreasing the abundance of RNAs encoding the structural proteins while increasing levels of viral RNAs encoding the regulatory proteins.
Web ID
– HY-139850
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C13H5F6N3OS2
References
– [1]Zamiri M, et al. 2-Trifluoromethylthiazole-5-carboxamides: Analogues of a Stilbene-Based Anti-HIV Agent that Impact HIV mRNA Processing. ACS Med Chem Lett. 2021 Oct 29;12(11):1818-1823.
CAS Number
– 2655502-29-5
Molecular Weight
– 397.32
SMILES
– O=C(NC1=NC(C=CC(C(F)(F)F)=C2)=C2S1)C3=CN=C(C(F)(F)F)S3
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
