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Products Details
Product Description
– gp120-IN-2 (compound 4i) is a potent HIV-1 gp120 inhibitor with an IC50 of 7.5 µM and CC50 of 112.93 µM. gp120-IN-2 shows anti-HIV-1 activity. gp120-IN-2 shows cytotoxicity in a dose dependent manner in SUP-T1 cells[1].
Web ID
– HY-144731
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C15H18N2O5
References
– [1]Senapathi J, et al. Design, Synthesis, and Antiviral activity of 1,2,3,4-Tetrahydropyrimidine derivatives acting as novel entry inhibitors to target at “Phe43 cavity” of HIV-1 gp120. Bioorg Med Chem. 2021 Dec 15;52:116526.
CAS Number
– 123629-42-5
Molecular Weight
– 306.31
SMILES
– CCOC(C1=C(NC(NC1C2=CC(OC)=C(C=C2)O)=O)C)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– HIV
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
