Download Files:
Gosogliptin
$360 – $2,160
Products Details
Product Description
– Gosogliptin is a potent and selective inhibitor of dipeptidyl peptidase-IV (DPP-IV).
Web ID
– HY-10287
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C17H24F2N6O
References
– [1]Dai H, et al. The pharmacokinetics of PF-734200, a DPP-IV inhibitor, in subjects with renal insufficiency. Br J Clin Pharmacol. 2011 Jul;72(1):85-91.|[2]Sharma R, et al. Metabolism, excretion, and pharmacokinetics of ((3,3-difluoropyrrolidin-1-yl)((2S,4S)-4-(4-(pyrimidin-2-yl)piperazin-1-yl)pyrrolidin-2-yl)methanone, a dipeptidyl peptidase inhibitor, in rat, dog and human. Drug Metab Dispos. 2012 Nov;40(11):2143-61.
CAS Number
– 869490-23-3
Molecular Weight
– 366.41
Compound Purity
– 99.27
SMILES
– O=C([C@H](C1)NC[C@H]1N2CCN(CC2)C3=NC=CC=N3)N4CC(CC4)(F)F
Clinical Information
– Phase 3
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– Dipeptidyl Peptidase
Isoform
– DPP-4
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
