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Goserelin (acetate)

$84$640

Products Details

Product Description

– Goserelin acetate (ICI-118630 acetate), a decapeptide analogue of gonadotropin-releasing hormone (GnRH/LHRH), functions as a GnRH agonist. Goserelin acetate can be used for the research of breast cancer, epithelial ovarian cancer and prostate cancer[1][2].

Web ID

– HY-13673A

Storage Temperature

– -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C61H88N18O16

References

– [1]Ning Zhang, et al. Goserelin promotes the apoptosis of epithelial ovarian cancer cells by upregulating forkhead box O1 through the PI3K/AKT signaling pathway. Oncol Rep. 2018 Mar; 39(3): 1034–1042.|[2]Halle C F Moore, et al. Goserelin for ovarian protection during breast-cancer adjuvant chemotherapy. N Engl J Med. 2015 Mar 5;372(10):923-32.

CAS Number

– 145781-92-6

Molecular Weight

– 1329.46

Compound Purity

– 99.92

SMILES

– O=C(N[C@H](C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@H](COC(C)(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N2CCC[C@H]2C(NNC(N)=O)=O)=O)=O)=O)=O)=O)CO)[C@@H](NC([C@H](CC3=CN=CN3)NC([C@@H](N4)CCC4=O)=O)=O)CC5=CNC6=C5C=CC=C6.CC(O)=O

Clinical Information

– Launched

Research Area

– Endocrinology; Cancer

Solubility

– DMSO : ≥ 28 mg/mL|H2O : 100 mg/mL (ultrasonic)

Target

– Apoptosis;GnRH Receptor

Pathway

– Apoptosis;GPCR/G Protein

Product type

– Peptides

Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.

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