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Products Details
Product Description
– GNE-6893 is a potent and orally active HPK1 inhibitor. GNE-6893 can be used in research of cancer[1].
Web ID
– HY-149056
Shipping
– Room temperature
Molecular Formula
– C23H24FN5O4
References
– [1]Andreas S, et, al. A Convergent Synthesis of HPK1 Inhibitor GNE-6893 via Palladium-Catalyzed Functionalization of a Tetrasubstituted Isoquinoline. Org. Process Res. Dev. 2023;27(3):523-9.
CAS Number
– 2415374-98-8
Molecular Weight
– 453.47
SMILES
– FC1=C(N)C(C=NC(NC(O[C@@H]2[C@H](COC2)C)=O)=C3)=C3C=C1C4=CN=C(OCCN5)C5=C4C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– MAP4K
Isoform
– MAP4K1/HPK1
Pathway
– MAPK/ERK Pathway
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
