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Products Details
Product Description
– Glycine-d3 is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.
Web ID
– HY-Y0966S10
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C2H2D3NO2
References
– [1]Johnson JW, et al. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 1987 Feb 5-11;325(6104):529-31.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 4896-76-8
Molecular Weight
– 78.09
SMILES
– O=C(O[2H])CN([2H])[2H]
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite, iGluR, Isotope-Labeled Compounds
Isoform
– NMDA Receptor
Pathway
– Membrane Transporter/Ion Channel, Metabolic Enzyme/Protease, Neuronal Signaling, Others
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
