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Products Details
Product Description
– Glycine-13C2,15N,d2 is the deuterium, 13C and 15N labeled Glycine[1]. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors[2].
Web ID
– HY-Y0966S11
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– 13C2H3D2 15NO2
References
– [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Johnson JW, et al. Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature. 1987 Feb 5-11;325(6104):529-31.
CAS Number
– 1984075-49-1
Molecular Weight
– 80.06
SMILES
– [15NH2][13C]([2H])([2H])[13C](O)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Endogenous Metabolite, iGluR
Pathway
– Membrane Transporter/Ion Channel, Metabolic Enzyme/Protease, Neuronal Signaling
Product type
– Isotope-Labeled Compounds
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