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Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
$125 – $185
Products Details
Product Description
– Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH is an ADC Linker that can be used to synthesize Drug-Linker Conjugates for ADC. Especially for the synthesis of Deruxtecan (HY-13631E), a toxic drug-linker conjugate[1].
Web ID
– HY-45672
Storage Temperature
– 4°C (Powder, stored under nitrogen, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C18H25N5O7
References
– [1]Masuda,et al. Preparation of antibody-drug conjugates for cancer therapy. World Intellectual Property Organization, WO2014057687 A1. 2014-04-17.
CAS Number
– 1599440-20-6
Molecular Weight
– 423.42
Compound Purity
– 99.02
SMILES
– OC(COCNC(CNC([C@@H](NC(CNC(CN)=O)=O)CC1=CC=CC=C1)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 1 mg/mL (ultrasonic;warming;heat to 60°C)|DMSO : 100 mg/mL (ultrasonic)|DMSO : 3 mg/mL (ultrasonic;warming;heat to 80°C)
Target
– ADC Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
