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Glutaminyl Cyclase Inhibitor 5
SKU
HY-152031-Get quote
Category Reference compound
Tags Amyloid-β, Neurological Disease, Neuronal Signaling
Products Details
Product Description
– Glutaminyl Cyclase Inhibitor 5 (Compound 71) is a potent and selective human glutaminyl cyclase (hQC) inhibitor with an IC50 of 3.2 nM[1].
Web ID
– HY-152031
Shipping
– Room temperature
Molecular Formula
– C22H30N6O
References
– [1]Van Manh N, et al. Discovery of potent indazole-based human glutaminyl cyclase (QC) inhibitors as Anti-Alzheimer’s disease agents. Eur J Med Chem. 2022 Dec 15;244:114837.
Molecular Weight
– 394.51
SMILES
– CC1=CN=CN1CCCNC(N(C2CCCCC2)C3=CC4=C(C(C)=NN4)C=C3)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Amyloid-β
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.