Products Details

Product Description

– GLUT1-IN-1 is a glucose transporter 1 (GLUT1) inhibitor and has a GLUT1-specific inactivation ability. GLUT1-IN-1 exhibits concentration-dependent cytotoxicity for HeLa, A549 and HepG2 cells with IC50 values of 5.49 μM, 11.14 μM, and 8.73 μM, respectively. GLUT1-IN-1 can be used for the research of photodynamic therapy (PDT) and severals cancer[1].

Web ID

– HY-151486

Shipping

– Room temperature

Applications

– Cancer-programmed cell death

Molecular Formula

– C25H31BF2I2N6O7

References

– [1]Kazuki Miura, et al. Photodynamic Therapy by Glucose Transporter 1-Selective Light Inactivation. ACS Omega Article ASAP.

Molecular Weight

– 830.17

SMILES

– OC[C@@H]1[C@H]([C@@H]([C@H]([C@@H](O1)OCCN2N=NC(CNC(CCC3=[N]4C(C=C3I)=CC5=C(C(I)=C(N5B4(F)F)C)C)=O)=C2)O)O)O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– GLUT

Isoform

– GLUT1

Pathway

– Membrane Transporter/Ion Channel

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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