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GLUT inhibitor-1
$780 – $6,500
Products Details
Product Description
– GLUT inhibitor-1 is a potent and orally active inhibitor of glucose transporters, targeting both GLUT1 and GLUT3, with IC50s of 242 nM and 179 nM, respectively. GLUT inhibitor-1 has the potential for the reaesrch of cancers and autoimmune diseases[1].
Web ID
– HY-139605
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C32H35N7O2
References
– [1]Liu KG, et al. Discovery and Optimization of Glucose Uptake Inhibitors. J Med Chem. 2020;63(10):5201-5211.
CAS Number
– 2421141-40-2
Molecular Weight
– 549.67
Compound Purity
– 98.01
SMILES
– O=C(COC1=CC=CC(C2=NC(CCN(C3CCC3)C4)=C4C(NC5=CC=C(C6=CNN=C6)C=C5)=N2)=C1)NC7(CC7)C
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– GLUT
Isoform
– GLUT1;GLUT3
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
