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Products Details
Product Description
– Glucocorticoids receptor agonist 2 is a potent anti-inflammatory, arylpyrazole-based glucocorticoid receptor agonist that does not impair insulin secretion.
Web ID
– HY-139710
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C25H25FN2O
References
– [1]Kennedy BJ, et al. Potent Anti-Inflammatory, Arylpyrazole-Based Glucocorticoid Receptor Agonists That Do Not Impair Insulin Secretion. ACS Med Chem Lett. 2021 Sep 15;12(10):1568-1577.
CAS Number
– 614761-20-5
Molecular Weight
– 388.48
SMILES
– O[C@H]([C@@]1([H])CCCC2=CC3=C(C[C@@]21C)C=NN3C4=CC=C(F)C=C4)C5=CC=CC=C5
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Glucocorticoid Receptor
Pathway
– Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
