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Glucocorticoid receptor agonist-2
$850
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Products Details
Product Description
– Glucocorticoid receptor agonist-2 (compound 21) is an glucocorticoid receptor agonist with an IC50 value of 6.6 nM. Glucocorticoid receptor agonist-2 can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference of ABBV-3373[1].
Web ID
– HY-148435
Storage Temperature
– -20°C (Powder, protect from light)
Shipping
– Blue Ice
Molecular Formula
– C34H35F2NO7
References
– [1]Mcpherson MJ, et al. Preparation of glucocorticoid receptor agonist and immunoconjugates thereof. WO2017210471. 2017.
CAS Number
– 2166378-92-1
Molecular Weight
– 607.64
Compound Purity
– 99.65
SMILES
– [H][C@]1(C[C@]2(O[C@H](O[C@]23C(CO)=O)C4=CC=C(OC5=CC(N)=CC=C5)C=C4)[H])[C@@]6(C[C@@H](C7=CC(C=C[C@@]7([C@](F)6[C@@H](O)C[C@@]13C)C)=O)F)[H]
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Glucocorticoid Receptor
Pathway
– Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
