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Glucocorticoid receptor agonist-1 Ala-Ala-Mal
$300 – $2,400
Products Details
Product Description
– Glucocorticoid receptor agonist-1 Ala-Ala-Mal (compound 88) is a glucocorticosteroid, and an agonist of glucocorticoid receptor. Glucocorticoid receptor agonist-1 Ala-Ala-Mal can be conjugated with Adalimumab (HY-P9908) to prepare an ADC[1].
Web ID
– HY-137882
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C48H54N4O11
References
– [1]McPherson, et al. Preparation of glucocorticoid receptor agonist and immunoconjugates thereof: World Intellectual Property Organization, WO2017210471[P]. 2017-12-07.
CAS Number
– 2166376-51-6
Molecular Weight
– 862.96
Compound Purity
– 99.94
SMILES
– O=C([C@]([C@@]1([H])C[C@@]2([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(C=C4)C)([H])[C@H]5O)(O[C@@](C(C=C6)=CC=C6CC7=CC(NC([C@H](C)NC([C@H](C)NC(CCN(C8=O)C(C=C8)=O)=O)=O)=O)=CC=C7)([H])O1)[C@]2(C5)C)CO
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 100 mg/mL (ultrasonic)|H2O : ≥ mg/mL
Target
– Drug-Linker Conjugates for ADC;Glucocorticoid Receptor
Pathway
– Antibody-drug Conjugate/ADC Related;Immunology/Inflammation;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
