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GLP-1R agonist 9
Products Details
Product Description
– GLP-1R agonist 9 (Compound 96) is a GLP-1R agonist with EC50 values of 1.1 nM and 11 nM against CHO GLP-1R Clone H6 and CHO GLP-1R Clone C6, respectively[1].
Web ID
– HY-147622
Shipping
– Room temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C32H30ClF2N3O5
References
– [1]Gary E. Aspnes, et al. Combinations comprising benzodioxol as glp-1r agonists for use in the treatment of nash/nafld and related diseases. WO2020234726A1.
CAS Number
– 2401894-00-4
Molecular Weight
– 610.05
SMILES
– FC1=C2C(O[C@](O2)(C3=C(C=C(C=C3)Cl)F)C)=C(C4CCN(CC4)CC(N(C5=C6)C[C@@H]7CCO7)=NC5=CC=C6C(O)=O)C=C1
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease
Solubility
– 10 mM in DMSO
Target
– GCGR
Pathway
– GPCR/G Protein
Product type
– Reference compound
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