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Gln-AMS
SKU
HY-112861-1 mg
Category Reference compound
Tags Aminoacyl-tRNA Synthetase;Bacterial, Anti-infection;Metabolic Enzyme/Protease, Infection
$180 – $850
Products Details
Product Description
– Gln-AMS is an aminoacyl-tRNA synthetases (AARS) inhibitor, which binds the A-domain within the NRPS enzymes.
Web ID
– HY-112861
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C15H22N8O8S
References
– [1]Fang P, et al. Structural basis for full-spectrum inhibition of translational functions on a tRNA synthetase. Nat Commun. 2015 Mar 31;6:6402.|[2]Atta-ur-Rahman, et al. Frontiers in Natural Product Chemistry.
CAS Number
– 209543-57-7
Molecular Weight
– 474.45
Compound Purity
– 99.21
SMILES
– NC1=C2N=CN([C@@H]3O[C@H](COS(=O)(NC([C@@H](N)CCC(N)=O)=O)=O)[C@@H](O)[C@H]3O)C2=NC=N1
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– DMSO : 120 mg/mL (ultrasonic)
Target
– Aminoacyl-tRNA Synthetase;Bacterial
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.