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Products Details
Product Description
– GlcN-6-P Synthase-IN-1 (Compound 4d) is a Glucosamine-6-phosphate (GlcN-6-P) synthase inhibitor with an IC50 of 3.47 μM. GlcN-6-P Synthase-IN-1 exhibits significant antimicrobial activity. GlcN-6-P Synthase-IN-1 has good penetration in the CNS and is able to inhibit the cytochrome P450, CYP3A4 isoform[1].
Web ID
– HY-147999
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H21N7S
References
– [1]Omar AM, et al. The rational design, synthesis, and antimicrobial investigation of 2-Amino-4-Methylthiazole analogues inhibitors of GlcN-6-P synthase. Bioorg Chem. 2020 Jun;99:103781.
CAS Number
– 2447602-44-8
Molecular Weight
– 391.49
SMILES
– C/C(C1=C(C)N=C(N/N=C/C2=CC=C(C3=CC=CC=C3)C=C2)S1)=NNC(N)=N
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial;Cytochrome P450;Fungal
Isoform
– CYP3
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
