Download Files:
Gilmelisib
$510 – $4,200
Products Details
Product Description
– Gilmelisib is an antineoplastic. Gilmelisib is a PI3K inhibitor (IC50 <1 nM for PI3K p110α) extracted from WO2017101847 A1, compound 1[1][2].
Web ID
– HY-139412
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C24H23ClFN5O5S
References
– [1]International Nonproprietary Names for Pharmaceutical Substances (INN)|[2]WO2017101847 A1
CAS Number
– 1845777-61-8
Molecular Weight
– 547.99
Compound Purity
– 99.62
SMILES
– O=S(C1=CC=C(F)C=C1Cl)(NC2=CC(C3=CN(C(C=C3)=NC=C4OCCN(C)C)C4=O)=CN=C2OC)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 5 mg/mL (ultrasonic;warming;adjust pH to 4 with HCl;heat to 60°C)
Target
– PI3K
Isoform
– PI3Kα
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
