Products Details

Product Description

– GGGDTDTC-Mc-vc-PAB-MMAE is a Drug-Linker Conjugate for ADC, containing a tubulin inhibitor Monomethyl auristatin E (MMAE, HY-15162)[1].

Web ID

– HY-153428

Shipping

– Room temperature

Molecular Formula

– C93H146N20O29S

References

– [1]Zhao YJ, et al. Nanobody drug conjugate with high activity and application of GALA polypeptide in antibody drug conjugate. China, CN112807444 A. 2021-05-18.

Molecular Weight

– 2040.34

SMILES

– CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(N(C)[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N2[C@@]([C@H](OC)[C@@H](C)C(N[C@H](C)[C@@H](O)C3=CC=CC=C3)=O)([H])CCC2)=O)C)=O)=O)=O)C=C1)=O)=O)NC(CCCCCN4C(C(SC[C@@H](C(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(O)=O)NC(CNC(CNC(CN)=O)=O)=O)=O)=O)=O)=O)CC4=O)=O)=O

Clinical Information

– No Development Reported

Research Area

– Cancer

Solubility

– 10 mM in DMSO

Target

– Drug-Linker Conjugates for ADC;Microtubule/Tubulin

Pathway

– Antibody-drug Conjugate/ADC Related;Cell Cycle/DNA Damage;Cytoskeleton

Product type

– ADC Related

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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