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Genistin
SKU
HY-N0595-10 mg
Category Natural Products
Tags Apoptosis;Estrogen Receptor/ERR, Apoptosis;Vitamin D Related/Nuclear Receptor, Cancer; Metabolic Disease
$55 – $176
Products Details
Product Description
– Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway[1][2][3].
Web ID
– HY-N0595
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C21H20O10
References
– [1]Choi YR, et al. Genistin: A Novel Potent Anti-Adipogenic and Anti-Lipogenic Agent. Molecules. 2020;25(9):2042. Published 2020 Apr 27.|[2]Liang Y, et al. A Comprehensive Screening and Identification of Genistin Metabolites in Rats Based on Multiple Metabolite Templates Combined with UHPLC-HRMS Analysis. Molecules. 2018;23(8):1862. Published 2018 Jul 26.|[3]Hwang ST, et al. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway [published online ahead of print, 2020 Oct 16]. Life Sci. 2020;263:118594.
CAS Number
– 529-59-9
Molecular Weight
– 432.38
Compound Purity
– 98.04
SMILES
– O=C(C(C1=CC=C(O)C=C1)=COC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)=C4)C2=C4O
Clinical Information
– No Development Reported
Research Area
– Cancer; Metabolic Disease
Solubility
– DMSO : ≥ 100 mg/mL
Target
– Apoptosis;Estrogen Receptor/ERR
Pathway
– Apoptosis;Vitamin D Related/Nuclear Receptor
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.