Download Files:
GDC-4379
$680 – $5,600
Products Details
Product Description
– GDC-4379 is a JAK1 inhibitor that can be used for the research of asthma[1].
Web ID
– HY-139837
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H18ClF2N7O3
References
– [1]Stumpf A, et, al. Efficient, Protecting Group Free Kilogram-Scale Synthesis of the JAK1 Inhibitor GDC-4379. Org. Process Res. Dev. 2021, 25, 11, 2537-2550.
CAS Number
– 2252277-73-7
Molecular Weight
– 489.86
Compound Purity
– 99.51
SMILES
– O=C(C1=C2N=CC=CN2N=C1)NC3=CN(CC(N(C)C)=O)N=C3C4=CC(Cl)=CC=C4OC(F)F
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 31.25 mg/mL (ultrasonic)
Target
– JAK
Pathway
– Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
