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GC7 Sulfate
$60 – $580
Products Details
Product Description
– GC7 Sulfate is a deoxyhypusine synthase (DHPS) inhibitor.
Web ID
– HY-108314A
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C8H22N4O4S
References
– [1]Lou B, et al. N1-guanyl-1,7-diaminoheptane (GC7) enhances the therapeutic efficacy of doxorubicin by inhibiting activation of eukaryotic translation initiation factor 5A2 (eIF5A2) and preventing the epithelial-mesenchymal transition in hepatocellular carcinoma cells. Exp Cell Res. 2013 Oct 15;319(17):2708-17.|[2]Bandino A, et al. Deoxyhypusine synthase (DHPS) inhibitor GC7 induces p21/Rb-mediated inhibition of tumor cell growth and DHPS expression correlates with poor prognosis in neuroblastoma patients. Cell Oncol (Dordr). 2014 Dec;37(6):387-98.
CAS Number
– 150417-90-6
Molecular Weight
– 270.35
Compound Purity
– 98.0
SMILES
– NC(NCCCCCCCN)=N.O=S(O)(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– H2O : 3 mg/mL (ultrasonic;warming)
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
