Download Files:
Ganfeborole (hydrochloride)
$550 – $2,700
Products Details
Product Description
– Ganfeborole hydrochloride (GSK656) is a potent antitubercular agent, acting as an inhibitor of Mycobacterium tuberculosis (Mtb) leucyl-tRNA synthetase (LeuRS), with an IC50 of 0.2 μM.
Web ID
– HY-107775
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C10H14BCl2NO4
References
– [1]Li X, et al. Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656). J Med Chem. 2017 Oct 12;60(19):8011-8026.
CAS Number
– 2131798-13-3
Molecular Weight
– 293.94
Compound Purity
– 99.88
SMILES
– OB1O[C@H](CN)C2=C(Cl)C=CC(OCCO)=C21.[H]Cl
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– DMSO : 67.5 mg/mL (ultrasonic)
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
