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Products Details
Product Description
– Ganfeborole (GSK656 free base) is a potent, selective and orally active inhibitor of M. tuberculosis leucyl-tRNA synthetase, with an IC50 of 0.20 μM. Ganfeborole can be used for the research of tuberculosis[1].
Web ID
– HY-134648
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C10H13BClNO4
References
– [1]Li X, et, al. Discovery of a Potent and Specific M. tuberculosis Leucyl-tRNA Synthetase Inhibitor: (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol (GSK656). J Med Chem. 2017 Oct 12;60(19):8011-8026.
CAS Number
– 2131798-12-2
Molecular Weight
– 257.48
SMILES
– OB1O[C@H](CN)C2=C(Cl)C=CC(OCCO)=C21
Clinical Information
– Phase 2
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Bacterial
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
