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Galnon
SKU
HY-103536-Get quote
Category Reference compound
Tags GPCR/G Protein;Neuronal Signaling, Neurological Disease, Neuropeptide Y Receptor
Products Details
Product Description
– Galnon is a selective and non-peptide agonist of galanin GAL1 and GAL2 receptor, with Kis of 11.7 and 34.1 μM respectively. Galnon exhibits anticonvulsant and anxiolytic effects[1][2].
Web ID
– HY-103536
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C40H46N4O6
References
– [1]Bartfai T, et, al. Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10470-5.|[2]Rajarao SJR, et, al. Anxiolytic-like activity of the non-selective galanin receptor agonist, galnon. Neuropeptides. 2007 Oct;41(5):307-20.
CAS Number
– 475115-35-6
Molecular Weight
– 678.82
SMILES
– O=C(N[C@H](C(N[C@@H](CCCCN)C(NC1=CC=C(C(C)=C2)C(OC2=O)=C1)=O)=O)CC3CCCCC3)OCC4C5=CC=CC=C5C6=CC=CC=C46
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Neuropeptide Y Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.