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GalNAc unconjugated/naked Fitusiran
$980
Only 1000 item(s) left in stock.
Products Details
Product Description
– GalNAc unconjugated/naked Fitusiran, an small interfering RNA without GalNAc conjugation, specifically targets antithrombin (AT) messenger RNA to lower production of AT in the liver. GalNAc unconjugated/naked Fitusiran increases thrombin generation and has the potential for the research of the hemophilia[1].
Web ID
– HY-150224
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– N/A
References
– [1]Pasi KJ, et al. Targeting of antithrombin in hemophilia A or B with investigational siRNA therapeutic fitusiran-Results of the phase 1 inhibitor cohort. J Thromb Haemost. 2021;19(6):1436-1446.
Molecular Weight
– 14459.60
Compound Purity
– 97.93
SMILES
– [GalNAc unconjugated/naked Fitusiran]
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in H2O
Target
– Factor Xa;Small Interfering RNA (siRNA)
Pathway
– Epigenetics;Metabolic Enzyme/Protease
Product type
– Oligonucleotides
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
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