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Galegine (hydrochloride)
$200 – $350
Products Details
Product Description
– Galegine hydrochloride, a guanidine derivative, contributes to weight loss in mice. Guanidine hydrochloride is the compound derived from G. officinalis, which gave rise to the biguanides, metformin and phenformin. Galegine hydrochloride activates AMPK in 3T3-L1 adipocytes and L6 myotubes, as well as in the H4IIE rat hepatoma and HEK293 human kidney cell lines. Galegine hydrochloride has antibacterial activity, with minimum inhibitory concentration of 4 mg/L against Staphylococcus aureus strains[1][2].
Web ID
– HY-N0930B
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C6H14ClN3
References
– [1]Mooney MH, et al. Mechanisms underlying the metabolic actions of galegine that contribute to weight loss in mice. Br J Pharmacol. 2008 Apr;153(8):1669-77.|[2]Coqueiro A, et al. In Vitro Antibacterial Activity of Prenylated Guanidine Alkaloids from Pterogyne nitens and Synthetic Analogues. J Nat Prod. 2014 Aug 22;77(8):1972-5.
CAS Number
– 2368870-39-5
Molecular Weight
– 163.65
Compound Purity
– 97.0
SMILES
– NC(NC/C=C(C)C)=N.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Infection; Metabolic Disease
Solubility
– DMSO : 5.2 mg/mL (ultrasonic)|H2O : 43.33 mg/mL (ultrasonic)
Target
– AMPK;Bacterial
Pathway
– Anti-infection;Epigenetics;PI3K/Akt/mTOR
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
