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Galectin-8-IN-1
Products Details
Product Description
– Galectin-8-IN-1 is a selective ligand for the galectin-8 N-terminal domain (galectin-8N), with a Kd of 48 μM and 15-fold selectivity over galectin-3 and even better selectivity over the other mammalian galectins.
Web ID
– HY-139831
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C16H18N2O6
References
– [1]Hassan M, et al. Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain. ACS Med Chem Lett. 2021 Nov 2;12(11):1745-1752.
Molecular Weight
– 334.32
SMILES
– O[C@H]1[C@@H](CO)OC=C[C@H]1OCC2=NC3=C(C=C(C(O)=O)C=C3)N2C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Galectin
Isoform
– Galectin-8
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.