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Products Details
Product Description
– Galectin-3/galectin-8-IN-2 (Compound 57) is a dual Galectin-3 and galectin-8 C-terminal domain inhibitor, with Kd values of 12.8 μM and 2.06 μM respectively. Galectin-3/galectin-8-IN-2 inhibits the MRC-5 lung fibroblast cells migration. Galectin-3/galectin-8-IN-2 can be used for research of cancer and tissue fibrosis[1].
Web ID
– HY-155192
Shipping
– Room temperature
Molecular Formula
– C26H18Cl2N2O4S2
References
– [1]Haoming Zhang, et al. Discovery of N-Arylsulfonyl-Indole-2-Carboxamide Derivatives as Galectin-3 and Galectin-8 C-Terminal Domain Inhibitors. ACS Med. Chem. Lett. 2023, 14, 9, 1257-1265.
Molecular Weight
– 557.47
SMILES
– O=C(C(N1)=CC2=C1C=CC(OC3=CC=C(Cl)C(Cl)=C3)=C2)NS(=O)(C4=C(CC5=CC=CC=C5)C=CS4)=O
Clinical Information
– No Development Reported
Research Area
– Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Galectin
Isoform
– Galectin-3;Galectin-8
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
